JAPANESE ANGELICA ROOT
EXTRACT BG-J

Lightening Lightening Anti-aging Anti-aging External irritants External irritants Japan origin Japan origin Clinical data Clinical data

Melanin dispersion Camouflage effects of age spots via the mechanism of melanosome degradation

  • JAPANESE ANGELICA ROOT EXTRACT BG-J

    Melanin dispersion - camouflage effects of age spots via the mechanism of melanosome degradation by promoting cathepsin activity.

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Mechanism

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Product information

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Product name JAPANESE ANGELICA ROOT EXTRACT BG-J
Scientific name Angelica acutiloba Kitagawa
Plant name (Japanese) トウキ, 当帰
Part of use Root
INCI JSQI name IECIC 2021 CAS#
Angelica Acutiloba Root Extract トウキエキス(1) 东当归(ANGELICA ACUTILOBA)根提取物 164288-49-7
Butylene Glycol 1,3- ブチレングリコール 丁二醇 107-88-0
Water 7732-18-5

Study

Clinical data

A positive change was confirmed by 2% JAPANESE ANGELICA ROOT EXTRACT BG-J cream application on the test area with an age spot.

In vitro data

Melanin dispersion / Skin lightening
  • Promoting effect on total cathepsins activity in keratinocyte
  • Promoting effect on cathepsin K/L2 mRNA expression in keratinocyte
  • Promoting effect on cathepsin L2 production in 3D skin model
  • Promoting effect on cathepsin K activity in keratinocyte containing melanosome
  • Promoting effect on melanosome digestion in keratinocyte containing melanosome

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