LEMON BALM EXTRACT RA

Anti-aging Anti-aging Sensitive skin Sensitive skin Japan origin Japan origin Clinical data Clinical data HALAL HALAL COSMOS COSMOS

Collagen Sustainability New approach to photoaging
Advancing collagen remodeling

  • LEMON BALM EXTRACT RA

    Collagen Sustainability - an advanced approach to preventing and postponing photoaging by promoting Endo180 production for collagen remodelling.

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Features

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    Clear traceability from cultivation, research to production

    • Our own recycling farm "Kui Farm" (Mihara city, Hiroshima, Japan)
    • Utilization of extraction residue after production of plant extracts
    • Cultivation by our company staff
    • Establishment of cultivation method (best harvest timing, stable, rosmarinic acid content)

    information icon Note

    For stable supply of this product, lemon balm is cultivated via contract farming at other locations in Hiroshima prefecture as well as our own farm.

  • Mechanism

    Collagen Sustainability

    Damaged collagen in the extracellular matrix (ECM) results in wrinkle formation, while intracellular damaged collagen prevents wrinkle formation. The physical “transfer” of damaged collagen from the outside to the inside of fibroblasts by Endo180 is the key to advance collagen remodeling.

Product information

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Product name LEMON BALM EXTRACT RA
Scientific name Melissa officinalis
Plant name (Japanese) コウスイハッカ
Part of use Leaf (Hiroshima, Japan)
INCI JSQI name IECIC 2021 CAS#
Melissa Officinalis Leaf Extract メリッサエキス 香蜂花(MELISSA OFFICINALIS)叶提取物 84082-61-1
Butylene Glycol 1,3- ブチレングリコール 丁二醇 107-88-0
Water 精製水 7732-18-5

Study

Clinical data

After 8 weeks application, 2% LEMON BALM EXTRACT RA cream showed a visual improvement on wrinkles and a significant change rate in “Wrinkle grade” compared to the placebo cream.

In vitro data

Anti-aging
  • Promoting effect on Endo180 production
  • Recovery effect on collagen production under the influences of IL-1α
  • Combination effect with L-ascorbic acid 2-glucoside(A2G) on collagen production

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