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By way of our analysis technology and cutting edge evaluating methods, discovering raw materials and creating finished products gives us the opportunity to help you reach your goal.

Searching for natural raw materials

  • Purchasing commercially-available market products, cultivated products, from domestic and overseas sources
  • Procurement by domestic and overseas field research and exploration
  • Procurement by joint research

Searching for the best natural raw materials is the first step towards meeting customer's needs. Maruzen Pharmaceuticals Co., Ltd. is always striving to secure the highest quality raw materials from Japan and the rest of the world. Raw materials are always thoroughly examined for accurate scientific naming, usability and sustainable supplies.

Patent, literature, pharmaceutical affairs

  • Academic investigation involving assessment of research literature and search of specialized journals (e.g., components, actions, drug effects)
  • Patent search, patent filings, patent maintenance, registration of trademarks

In order to ensure customer safety, Maruzen Pharmaceuticals Co., Ltd. makes every effort to keep up-to–date with the latest news and information with regard to patents, scientific publications.

Analysis of active ingredients

  • Separation and purification of active ingredients (e.g., various carriers, HPLC)
  • Chemical structure analysis (NMR, LC-MS)
  • Analysis of active ingredients (e.g. HPLC, LC-MS)

In order to identify active ingredients and analyze components, we use NMR, LC-MS, and HPLC technology. We discover the active ingredient is discovered thorough separation and purification of each component, identifying its structure and measureing the concentration of the active ingredients.


  • Plant tissue culture
  • Plant meristem culture
  • Substance conversion using enzymes and microorganisms

Our bioresearch is heading toward discovering new ways of utilizing natural plants using enzymes and microorganisms and producing active ingredients by plant culture technology. It is our goal to produce effective natural materials of consistently stable quality.

Efficacy evaluation Safety evaluation

  • Evaluation of material efficacy/ pharmacological test
  • Safety evaluation
  • Human skin and hair test

We use more than 100 kinds of evaluations to confirm the safety of our products and discover the efficacies which natural plant materials posses. Our evaluation evidence proves Maruzen Pharmaceuticals Co., Ltd.'s commitment to producing safe and effective natural products for your use.

Evaluation of functional material and pharmacology tests

  • Antioxidant effects
  • Anti-aging effects on skin
  • Anti-inflammatory effects
  • Anti-allergic effects
  • Antimicrobial action
  • Anti- excessive weight gain
  • Anti-tumor and cancer-preventing effects
  • Immunostimulant effects
  • Osteoporosis-preventing effects
  • Cavity-prevention effects
  • Preventive effects against prostate hyperplasia
  • Energizing effects
  • Antihypertensive effects
  • Whitening effects
  • Hair growth effects
  • Deodorizing effects
  • Various enzyme inhibition tests, etc.

Safety evaluation

  • We are currently moving to adopt non-animal safety tests.
  • For ditails, please contact us.

Human skin and hair tests

  • Skin temperature and skin blood-flow measurement test (THERMOTRACER, Two-dimensional laser blood-flowmeter)
  • Skin moisture evaluation test (SKICON-200 EX, CORNEOMETER, TEWAMETER)
  • Skin elasticity evaluation test (CUTOMETER)
  • Skin permeability evaluation test (human skin three-dimensional model)
  • Hair smoothness evaluation test (friction tester), etc.

Extraction and supercritical extraction tests

  • Supercritical fluid extraction test
  • Membrane separation and purification tests
  • Column chromatography separation and purification tests
  • Crystallization separation and purification tests
  • Flavor retention tests, etc.

We always utilize the latest equipment and technology to break new ground in the area of extraction and purification.
This is another way in which our aims to produce unique and cutting-edge products.

Product development

  • Planning, proposal, and development of new products
  • Development of use (application)
  • Examination of manufacturing processes and development of new technologies
  • Joint research with clients (products, technologies)
  • Joint research with research centers and universities
  • Commissioned tests, commissioned research.

We obtain natural plant materials and work to create new products from these natural materials using our know-how and state-of-the-art technology for actual use of in pharmaceuticals, cosmetics, quasi-drugs and food. We are happy to work together with our clients to develop ideal products.

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